GREENVILLE

The Heart of Downtown Greenville

Join us for creative, scratch-made Southern food and spirits in Greenville’s vibrant downtown. 

Free Dessert for Mom this Mother's Day at Tupelo Honey Cafe

We understand the insanity and the joy that is being a mom. This Mother’s Day celebrate with a little relief from the kitchen and a “quiet” meal on us, including a special Mint Julep cocktail and free dessert for mom! Click here to learn more and and make a reservation.

View the Menu

  • Greenville

    1 N Main St Ste T
    Greenville, SC 29601
    Phone: 864-451-6200

    Take a Virtual Tour
    Map with Directions

  • Hours

    Monday – Thursday: 11 a.m. – 9 p.m.
    Friday & Saturday: 8 a.m. – 10 p.m.
    Sunday: 8 a.m. – 9 p.m.

    Brunch & Lunch: Open – 4 p.m.
    Dinner: 4 p.m. – Close
    Happy Hour: Mon. – Thurs. from 4 – 7 p.m.

  • Parking Options

    Click to see a Parking Map

Reservations

Tupelo Honey takes a limited number of reservations online for parties of 5 or less. Reservations can be made up to 2 hours prior to your desired arrival time. Most of our dining room is seated on a first come first serve basis.

For parties of 10 or more, please call the restaurant at 864-451-6200 and ask to speak with a manager.

 

Our Greenville Home

Located in the heart of downtown Greenville, Tupelo Honey Cafe is located between the Bank of America Building and Anthropologie. Our location is convenient to the Peace Center, Falls Park on the Reedy, Fluor Field, Liberty Bridge, the Swamp Rabbit Trail and all of the city’s charming downtown shops, galleries and hotels.

 

Our Food

What constitutes “New South Flavors?” For us, it is begins with reverence for those time-honored Southern dishes, served up by wonderful home cooks for years. We respect the freshness, the flavors and the food itself, but we like to jazz it up a little by adding something deliciously unexpected to delight your palate. Our interpretation of traditional Southern fare is creative, inventive and satisfyingly scrumptious. Cheers to New South Flavor!

Our Bar

Our roots in Asheville (Beer City USA) and love of Southern cocktails have inspired our appreciation for the art of imbibing. Our bar specializes in the best craft beers we can find and the most inventive, scratch-made Southern cocktails we can imagine. That includes our three different Bloody Marys, including our Queen Mary– perfect for brunch!

Located in the heart of downtown Greenville South Carolina.
Tupelo Honey Café Greenville features fresh, southern, scratch-made food.
Grilled Bone-in Pork Chop with Braised Figs and Red Wine Reduction
Shrimp and Goat Cheese Grits with caramelized onions and roasted red peppers
Craft beer, signature cocktails and sustainable wines at Tupelo Honey Café Greenville Bar.
Shaved Brussels sprouts salad with honey vinagrette.
Local artist Simone Wilson has art in all Tupelo Honey Cafes.
Carolina Peach Mai Tai with Muddy River Distillery Rum
Tupelo Farm Burger from Creekston Farms - all-natural and hormone free.
Sweet Potato Pancakes with spiced pecans and whipped peach butter.
Queen Bloody Mary with roasted yellow tomatoes and a killer garnish.
We source craft beer from the best breweries around the world.

Our Food

What constitutes “New South Flavors?” For us, it is begins with reverence for those time-honored Southern dishes, served up by wonderful home cooks for years. We respect the freshness, the flavors and the food itself, but we like to jazz it up a little by adding something deliciously unexpected to delight your palate. Our interpretation of traditional Southern fare is creative, inventive and satisfyingly scrumptious. Cheers to New South Flavor!

Our Bar

Our roots in Asheville (Beer City USA) and love of Southern cocktails have inspired our appreciation for the art of imbibing. Our bar specializes in the best craft beers we can find and the most inventive, scratch-made Southern cocktails we can imagine. That includes our three different Bloody Marys, including our Queen Mary– perfect for brunch!

 

Happy Hour