The Heart of Downtown Greenville
Join us for creative, scratch-made Southern food and spirits in Greenville’s vibrant downtown.
Don’t forget to come in for Happy Hour Monday – Thursday from 4 – 7 p.m. for $3 drafts, $4.50 snacks and $5 select cocktails!
1 N Main St Ste T
Greenville, SC 29601
Mon – Thurs: 11 am – 9 pm
Fri & Sat: 8 am – 10 pm
Sunday: 8 am – 9 pm
Brunch & Lunch: Open – 4 pm
Dinner: 4 pm – Close
Happy Hour: Mon – Thurs from 4 – 7 pm
Tupelo Honey takes a limited number of reservations online for parties of 4 or less. Reservations can be made up to 2 hours prior to your desired arrival time. Most of our dining room is seated on a first come first serve basis.
For parties of 5 or more, please call the restaurant at 864-451-6200 and ask to speak with a manager.
Our Greenville Home
Located in the heart of downtown Greenville, Tupelo Honey Cafe is located between the Bank of America Building and Anthropologie. Our location is convenient to the Peace Center, Falls Park on the Reedy, Fluor Field, Liberty Bridge, the Swamp Rabbit Trail and all of the city’s charming downtown shops, galleries and hotels.
What constitutes “New South Flavors?” For us, it is begins with reverence for those time-honored Southern dishes, served up by wonderful home cooks for years. We respect the freshness, the flavors and the food itself, but we like to jazz it up a little by adding something deliciously unexpected to delight your palate. Our interpretation of traditional Southern fare is creative, inventive and satisfyingly scrumptious. Cheers to New South Flavor!
Our roots in Asheville (Beer City USA) and love of Southern cocktails have inspired our appreciation for the art of imbibing. Our bar specializes in the best craft beers we can find and the most inventive, scratch-made Southern cocktails we can imagine. That includes our three different Bloody Marys, including our Queen Mary– perfect for brunch!