The heart of downtown Greenville beats for responsibly sourced Southern food that warms the soul. We’re located within an easy stroll of downtown Greenville’s charming shops, galleries, hotels and more.

Winner, Winner, Easter Dinner!

Join us for dinner on Easter Sunday and win a prize like dinner for four! Each table will have the chance to pick a card out of the basket for a prize to use on your next visit in April. Prizes include a free small plate, $10 off your purchase, dinner for four, and more!


GrubHub Delivery is now available in Greenville!

Tupelo Honey is now available through GrubHub! Have your favorite Southern dishes delivered right to your door.


Southern Comfort Starting at $13

When it's cold outside, your food should make you warm all over. Check out our Seasonal Special Entrees Sun-Wed starting at $13 after 4pm.

See the Specials

Tupelo To-Go Online Is Here!

Avoid the wait and order your favorite menu items online.

Order Online


1 N Main St Ste T
Greenville, SC 29601

Phone: 864-451-6200


M to Th: 10a – 9p
F: 10a – 10p
Sat: 8a – 10p
Sun: 8a – 9p

Brunch: Sat – Sun from Open – 4p
Happy Hour: Mon – Thurs from 4p – 7p