Welcome to Tupelo in...

Des Moines


  • MON-FRI: 11am-9pm
  • SAT: 9am-9pm
  • SUN: 9am-8pm

Special Features

Happy Hour

3 to 5:30PM, Monday through Friday

Outdoor Dining

Outdoor seating available on our spacious patio


Furry friends are welcome on the patio


Street & garage parking available nearby


Order online for pickup or delivery

Special Events

Let us host your next event!

Southern Food in Des Moines

Tupelo Honey Southern Kitchen & Bar is located in downtown Des Moines, Iowa.

Our restaurant serves scratch-made & responsibly sourced Southern food for brunch, lunch, and dinner. Our bar offers an extensive list of hand-crafted cocktails, wines, and local craft beers. Join us during Happy Hour every Monday through Friday for drink and food specials.

We are known for our superior Southern hospitality and welcoming atmosphere. Our menu has something for everyone, making us the perfect choice for a family dinner, date night, business lunch, special event, and more.


Thank You Kindly!

The latest press & awards for Tupelo Honey in Des Moines.

  • 100 Most Popular Brunch Spots in America


  • Vibrant Bar Scene

    OpenTable Diners Choice

  • Top 500 Restaurants